The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

X.o

Neutrophilic dermatosis (Pyoderma, Sweet syndrome)

Publications

Sivanandam LK, Begum B, Martinez EC, Garikipati S, Sanker V, Siddiq A

Azathioprine hypersensitivity: A Sweet-like syndrome.

International journal of rheumatic diseases. 2024;27(1):e14817

Arun Kumar AU, Elsayed ME, Alghali A, Ali AA, Mohamed H, Hussein W, Hackett C, Leonard N, Stack AG

Sweet syndrome: a rare feature of ANCA-associated vasculitis or unusual consequence of azathioprine-induced treatment.

Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology. 2018;14:46

El-Azhary RA, Brunner KL, Gibson LE

Sweet syndrome as a manifestation of azathioprine hypersensitivity.

Mayo Clinic proceedings. 2008;83(9):1026-30