The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLII.a

Alveolar hemorrhage (AH), diffuse AH (DAH)

Publications

Nour-Eldin NE, Naguib NN, Mack M, Abskharon JE, Vogl TJ

Pulmonary hemorrhage complicating radiofrequency ablation, from mild hemoptysis to life-threatening pattern.

European radiology 2011 Jan;21;197-204 — 2011 Jan — 197-204

Zhu JC, Yan TD, Morris DL

A systematic review of radiofrequency ablation for lung tumors.

Annals of surgical oncology 2008 Jun;15;1765-74 — 2008 Jun — 1765-74