The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

I.a

Pneumonitis (interstitial lung disease/ILD)

Publications

MORANDI L, OCHSNER H, NEUENSCHWANDER A

[Secondary manifestations in tuberculosis treatment with paraaminosalicylic acid].

Schweizerische medizinische Wochenschrift 1951 Dec 29;81;1301-5 — 1951 Dec 29 — 1301-5

JACKSON SL

Acute perifocal reaction in tuberculosis due to PAS.

Tubercle 1954 Aug;35;188-94 — 1954 Aug — 188-94