The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

VIII.a

Angioedema (may cause UAO, asphyxia and death)

Publications

Ducote C, Kesterke MJ, Bhattacharjee R, Read-Fuller A, Reddy LV

Macroglossia secondary to lisinopril-induced acute angioedema.

Proceedings (Baylor University. Medical Center). 2019;32(1):70-72

Soo Hoo GW, Lin HK, Junaid I, Klaustermeyer WB

Angiotensin-converting Enzyme Inhibitor Angioedema Requiring Admission to an Intensive Care Unit.

The American journal of medicine. 2015;128(7):785-9

Ferastraoaru D, Rosenstreich D, Jariwala S

Severe Angioedema Associated With Angiotensin-Converting Enzyme Inhibitor Therapy in Two Patients With Pollen-Food Allergy Syndrome.

Journal of clinical hypertension (Greenwich, Conn.). 2015;17(6):493-4

Leung E, Hanna MY, Tehami N, Francombe J

Isolated unilateral tongue oedema: the adverse effect of Angiotensin converting enzyme inhibitors.

Current drug safety. 2012;7(5):382-3

Norman JL, Holmes WL, Bell WA, Finks SW

Life-threatening ACE inhibitor-induced angioedema after eleven years on lisinopril.

Journal of pharmacy practice. 2013;26(4):382-8

Hom KA, Hirsch R, Elluru RG

Antihypertensive drug-induced angioedema causing upper airway obstruction in children.

International journal of pediatric otorhinolaryngology. 2012;76(1):14-9

Hussain N, Ahmed N, Ramjug S

A case of airway compromise.

BMJ (Clinical research ed.). 2010;341:c3822

Gutman I

Acutely swollen tongue in a middle-aged woman.

American family physician. 2010;82(3):279

Adebayo PB, Alebiosu OC

ACE-I induced angioedema: a case report and review of literature.

Cases journal. 2009;2:7181

Reed LK, Meng J, Joshi GP

Tongue swelling in the recovery room: a case report and discussion of postoperative angioedema.

Journal of clinical anesthesia. 2006;18(3):226-9

Shiber JR

Images in clinical medicine. Angioedema of the arytenoids.

The New England journal of medicine. 2005;353(17):e15

Krikorian RK, Quick A, Tal A

Angioedema following the intravenous administration of metoprolol.

Chest. 1994;106(6):1922-3

Kuo DC, Barish RA

Isolated uvular angioedema associated with ACE inhibitor use.

The Journal of emergency medicine. 1995;13(3):327-30

Noble TA, Murray KM

Lisinopril: a nonsulfhydryl angiotensin-converting enzyme inhibitor.

Clinical pharmacy. 1988;7(9):659-69

Seidman MD, Lewandowski CA, Sarpa JR, Potesta E, Schweitzer VG

Angioedema related to angiotensin-converting enzyme inhibitors.

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery. 1990;102(6):727-31

Ulmer JL, Garvey MJ

Fatal angioedema associated with lisinopril.

The Annals of pharmacotherapy. 1992;26(10):1245-6

Jain M, Armstrong L, Hall J

Predisposition to and late onset of upper airway obstruction following angiotensin-converting enzyme inhibitor therapy.

Chest. 1992;102(3):871-4