The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Tuberculosis (pulmonary, pulmonary, extrapulmonary or disseminated). Reactivation or de novo
Publications
Winthrop KL, Baxter R, Liu L, Varley CD, Curtis JR, Baddley JW, McFarland B, Austin D, Radcliffe L, Suhler E, Choi D, Rosenbaum JT, Herrinton LJ
Mycobacterial diseases and antitumour necrosis factor therapy in USA.
Annals of the rheumatic diseases 2013 Jan;72;37-42 — 2013 Jan — 37-42
Choice of Biologic Therapy for Patients with Rheumatoid Arthritis: The Infection Perspective.
Current rheumatology reviews 2011 Feb;7;77-87 — 2011 Feb — 77-87
Clinical image: Development of miliary tuberculosis following one intraarticular injection of etanercept.
Arthritis and rheumatism 2011 May;63;1364 — 2011 May — 1364