The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

I.a

Pneumonitis (interstitial lung disease/ILD)

Publications

Sumi T, Terai K, Suzuki K, Koshino Y, Ikeda T, Watanabe H, Yamada Y, Chiba H

Minocycline-induced Acute Fibrinous and Organizing Pneumonia.

American journal of respiratory and critical care medicine 2023 Dec 15;208;e47-e48 — 2023 Dec 15 — e47-e48

Barbagelata López C, Otero Palleiro MM, Seoane González B, Sánchez Vidal E

[Minocycline-induced hypersensitivity pneumonitis].

Medicina clinica 2007 Jan 20;128;79 — 2007 Jan 20 — 79

Rikken NE, Klinkhamer PJ, Haak HR

Interstitial pneumonia and hepatitis caused by minocycline.

The Netherlands journal of medicine 2004 Feb;62;62-4 — 2004 Feb — 62-4