The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

I.c

Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

Publications

Kampman A, Keulers L, der Maten JV, der Meij JV, Bethlehem C

A Severe Case of Isotretinoin Induced Eosinophilic Pneumonia and Pericardial Effusion, a Case Report.

Current drug safety 2024 Jan 24;; — 2024 Jan 24

De Giacomi F, Decker PA, Vassallo R, Ryu JH

Acute Eosinophilic Pneumonia: Correlation of Clinical Characteristics With Underlying Cause.

Chest 2017 08;152;379-385 — 2017 08 — 379-385

Oliviero G, Constans P, Caby I, De Rohan Chabot P, Lacherade JC

[Lung disease induced by isotretinoin].

Revue des maladies respiratoires 1995;12;631-3 — 1995 — 631-3