The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Pulmonary hypertension of the newborn (Persistent PHT)
Publications
Grigoriadis S, Vonderporten EH, Mamisashvili L, Tomlinson G, Dennis CL, Koren G, Steiner M, Mousmanis P, Cheung A, Ross LE
Prenatal exposure to antidepressants and persistent pulmonary hypertension of the newborn: systematic review and meta-analysis.
BMJ (Clinical research ed.) 2014 Jan 14;348;f6932 — 2014 Jan 14 — f6932
Pathophysiology, management, and outcome of persistent pulmonary hypertension of the newborn: a clinical review.
Frontiers in pediatrics 2013 Sep 02;1;23 — 2013 Sep 02 — 23
Safety of selective serotonin reuptake inhibitors in pregnancy.
CNS drugs 2009;23;493-509 — 2009 — 493-509