The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLIX.w

Multiple organ dysfunction/failure (MODS/MOF)

Publications

Carrillo-Esper R, González-Avila D, Uribe-Ríos M, Méndez-Sánchez N

Interstitial pneumonitis associated with pegylated interferon alpha-2b therapy for chronic hepatitis C: case report.

Annals of hepatology 2008 Jan-Mar;7;87-90 — 2008 Jan-Mar — 87-90

Abi-Nassif S, Mark EJ, Fogel RB, Hallisey RK

Pegylated interferon and ribavirin-induced interstitial pneumonitis with ARDS.

Chest 2003 Jul;124;406-10 — 2003 Jul — 406-10