The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLII.a

Alveolar hemorrhage (AH), diffuse AH (DAH)

Publications

Jeannin G, Mathieu S, Kemeny JL, Caillaud D, Soubrier M

Alveolar hemorrhage after infliximab therapy.

Joint, bone, spine : revue du rhumatisme 2010 Mar;77;189-90 — 2010 Mar — 189-90

Panagi S, Palka W, Korelitz BI, Taskin M, Lessnau KD

Diffuse alveolar hemorrhage after infliximab treatment of Crohn's disease.

Inflammatory bowel diseases 2004 May;10;274-7 — 2004 May — 274-7