The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

LI.d

Myocarditis (can be fulminant)

Publications

Jeremic I, Vujasinovic-Stupar N, Terzic T, Damjanov N, Nikolic M, Bonaci-Nikolic B

Fatal sulfasalazine-induced eosinophilic myocarditis in a patient with periodic fever syndrome.

Medical principles and practice : international journal of the Kuwait University, Health Science Centre 2015;24;195-7 — 2015 — 195-7

Lau G, Kwan C, Chong SM

The 3-week sulphasalazine syndrome strikes again.

Forensic science international 2001 Nov 01;122;79-84 — 2001 Nov 01 — 79-84