The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

I.e

Organizing pneumonia pattern (an area or areas of consolidation on imaging)

Publications

Sakaida H, Komase Y, Takemura T

Organizing pneumonia in a patient with rheumatoid arthritis treated with etanercept.

Modern rheumatology 2010 Dec;20;611-6 — 2010 Dec — 611-6

Hsu PC, Lan JL, Hsieh TY, Jan YJ, Huang WN

Methotrexate pneumonitis in a patient with rheumatoid arthritis.

Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 2003 Jun;36;137-40 — 2003 Jun — 137-40