The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Anaphylaxis-Anaphylactoid reaction (can be fatal)
Publications
Anaphylactic-like reaction to methylene blue: case report and review of perioperative hypersensitivity reactions.
Plastic and reconstructive surgery 2012 Jul;130;98e-105e — 2012 Jul — 98e-105e
Anaphylaxis reaction of a breast cancer patient to methylene blue during breast surgery with sentinel node mapping.
Acta oncologica (Stockholm, Sweden) 2010 Aug;49;877-8 — 2010 Aug — 877-8