The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

II.a

Pulmonary edema, noncardiogenic (NCPE)

Publications

Ibrahim J, Al Amri A, Ghatasheh G

Transfusion-Related Acute Lung Injury After Immunoglobulin Infusion for Kawasaki Disease: A Case Report and Literature Review.

Global pediatric health. 2017;4:2333794X17746545

Oykhman P, Hamilton MA, Aaron SL

Multiorgan Failure From Cryoglobulinemic Vasculitis Following Intravenous Immunoglobulin Replacement Therapy.

Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases. 2016;22(8):441-443

Quest GR, Gaal H, Clarke G, Nahirniak S

Transfusion-related acute lung injury after transfusion of pooled immune globulin: a case report.

Transfusion. 2014;54(12):3088-91

Rizk A, Gorson KC, Kenney L, Weinstein R

Transfusion-related acute lung injury after the infusion of IVIG.

Transfusion. 2001;41(2):264-8

Singh A, Biswal N, Nalini P, Sethuraman, Badhe A

Acute pulmonary edema as a complication of anti-snake venom therapy.

Indian journal of pediatrics. 2001;68(1):81-2

Suassuna JH, da Costa MA, Faria RA, Melichar AC

Noncardiogenic pulmonary edema triggered by intravenous immunoglobulin in cancer-associated thrombotic thrombocytopenic purpura-hemolytic uremic syndrome.

Nephron. 1997;77(3):368-70