The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XV.ag

Path: Foreign body embolism, microangiopathy, vasculopathy

Publications

Bhagat R, Forteza RM, Calcote CB, Williams WT, Bigler SA, Dwyer TM

Pulmonary emboli from therapeutic sodium hyaluronate.

Respiratory care. 2012;57(10):1670-3

Park HJ, Jung KH, Kim SY, Lee JH, Jeong JY, Kim JH

Hyaluronic acid pulmonary embolism: a critical consequence of an illegal cosmetic vaginal procedure.

Thorax. 2010;65(4):360-1