The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XVIII.c

BAL: An excess proportion of eosinophils

Publications

Dias OM, Nascimento ECTD, Chate RC, Kairalla RA, Baldi BG

Eosinophilic pneumonia: remember topical drugs as a potential etiology.

Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia 2018 Nov-Dec;44;522-524 — 2018 Nov-Dec — 522-524

Toyoshima M, Sato A, Hayakawa H, Taniguchi M, Imokawa S, Chida K

A clinical study of minocycline-induced pneumonitis.

Internal medicine (Tokyo, Japan) 1996 Mar;35;176-9 — 1996 Mar — 176-9

Sitbon O, Bidel N, Dussopt C, Azarian R, Braud ML, Lebargy F, Fourme T, de Blay F, Piard F, Camus P

Minocycline pneumonitis and eosinophilia. A report on eight patients.

Archives of internal medicine 1994 Jul 25;154;1633-40 — 1994 Jul 25 — 1633-40