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The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

X.f

Anaphylaxis-Anaphylactoid reaction (can be fatal)

Publications

Khalili B, Bardana EJ Jr, Yunginger JW

Psyllium-associated anaphylaxis and death: a case report and review of the literature.

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 2003;91(6):579-84

Vaswani SK, Hamilton RG, Valentine MD, Adkinson NF Jr

Psyllium laxative-induced anaphylaxis, asthma, and rhinitis.

Allergy. 1996;51(4):266-8

Zaloga GP, Hierlwimmer UR, Engler RJ

Anaphylaxis following psyllium ingestion.

The Journal of allergy and clinical immunology. 1984;74(1):79-80

Seggev JS, Ohta K, Tipton WR

IgE mediated anaphylaxis due to a psyllium-containing drug.

Annals of allergy. 1984;53(4):325-6

Sussman GL, Dorian W

Psyllium anaphylaxis.

Allergy proceedings : the official journal of regional and state allergy societies. 1990;11(5):241-2

Lantner RR, Espiritu BR, Zumerchik P, Tobin MC

Anaphylaxis following ingestion of a psyllium-containing cereal.

JAMA. 1990;264(19):2534-6

Gillespie BF, Rathbun FJ

Adverse effects of psyllium.

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne. 1992;146(1):16-7