Philippe Camus, M.D.

Dijon, France

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The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

I.a

Pneumonitis (interstitial lung disease/ILD)

Publications

Lager J, Hilberg O, Løkke A, Bendstrup E

Severe interstitial lung disease following treatment with certolizumab pegol: a case report.

European respiratory review : an official journal of the European Respiratory Society 2013 Sep 01;22;414-6 — 2013 Sep 01 — 414-6

Glaspole IN, Hoy RF, Ryan PF

A case of certolizumab-induced interstitial lung disease in a patient with rheumatoid arthritis.

Rheumatology (Oxford, England) 2013 Dec;52;2302-4 — 2013 Dec — 2302-4

Pearce F, Johnson SR, Courtney P

Interstitial lung disease following certolizumab pegol.

Rheumatology (Oxford, England) 2012 Mar;51;578-80 — 2012 Mar — 578-80