The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

LIX.e

Pneumocystis jiroveci pneumonia

Publications

Obeid KM, Aguilar J, Szpunar S, Sharma M, del Busto R, Al-Katib A, Johnson LB

Risk factors for Pneumocystis jirovecii pneumonia in patients with lymphoproliferative disorders.

Clinical lymphoma, myeloma & leukemia 2012 Feb;12;66-9 — 2012 Feb — 66-9

Anaissie EJ, Kontoyiannis DP, O'Brien S, Kantarjian H, Robertson L, Lerner S, Keating MJ

Infections in patients with chronic lymphocytic leukemia treated with fludarabine.

Annals of internal medicine 1998 Oct 01;129;559-66 — 1998 Oct 01 — 559-66