The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XVII.g

Tuberculosis (pulmonary, pulmonary, extrapulmonary or disseminated). Reactivation or de novo

Publications

Cappell MS, Saad A, Bortman JS, Amin M

Ileocolonic tuberculosis clinically, endoscopically, and radiologically mimicking Crohn's disease: disseminated infection after treatment with infliximab.

Journal of Crohn's & colitis. 2014;8(6):560-2

Koschny R, Junghanss T, Mischnik A, Karner M, Kreuter M, Roth W, Stremmel W, Merle U

Development of miliary tuberculosis under infliximab in a patient with spondyloarthritis and suspected Crohn's disease.

Zeitschrift fur Gastroenterologie. 2013;51(10):1177-83

Bruzzese V, Lorenzetti R, Zullo A, Campo SM, Hassan C

Intestinal tuberculosis mimicking Crohn disease in infliximab-treated rheumatoid arthritis.

Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases. 2012;18(6):324

Bass AR, Schneider R, Sanders A, Flieder D, Nathan CF, Erkan D

Pulmonary nodules in an infliximab-treated rheumatoid arthritis patient: a clinical pathology conference held by the Division of Rheumatology at Hospital for Special Surgery.

HSS journal : the musculoskeletal journal of Hospital for Special Surgery. 2007;3(1):119-25

Bourikas LA, Kourbeti IS, Koutsopoulos AV, Koutroubakis IE

Disseminated tuberculosis in a Crohn's disease patient on anti-TNF alpha therapy despite chemoprophylaxis.

Gut. 2008;57(3):425; author reply 425-6

Imaizumi K, Sugishita M, Usui M, Kawabe T, Hashimoto N, Hasegawa Y

Pulmonary infectious complications associated with anti-TNFalpha therapy (infliximab) for rheumatoid arthritis.

Internal medicine (Tokyo, Japan). 2006;45(10):685-8

Wolfe F, Michaud K, Anderson J, Urbansky K

Tuberculosis infection in patients with rheumatoid arthritis and the effect of infliximab therapy.

Arthritis and rheumatism. 2004;50(2):372-9

Gómez-Reino JJ, Carmona L, Valverde VR, Mola EM, Montero MD, BIOBADASER Group

Treatment of rheumatoid arthritis with tumor necrosis factor inhibitors may predispose to significant increase in tuberculosis risk: a multicenter active-surveillance report.

Arthritis and rheumatism. 2003;48(8):2122-7

Mayordomo L, Marenco JL, Gomez-Mateos J, Rejon E

Pulmonary miliary tuberculosis in a patient with anti-TNF-alpha treatment.

Scandinavian journal of rheumatology. 2002;31(1):44-5