The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

LVII.a

BAL: An excess proportion of lymphocytes

Publications

Amraoui K, Belhadj K, Maître B, Jannière-Nartey C, Dupuis J

Pulmonary toxicity after long-term treatment with lenalidomide in two myeloma patients.

European respiratory review : an official journal of the European Respiratory Society 2013 Mar 01;22;93-5 — 2013 Mar 01 — 93-5

Kunimasa K, Ueda T, Arita M, Maeda T, Hotta M, Ishida T

Drug-induced interstitial pneumonitis due to low-dose lenalidomide.

Internal medicine (Tokyo, Japan) 2012;51;1081-5 — 2012 — 1081-5

Thornburg A, Abonour R, Smith P, Knox K, Twigg HL

Hypersensitivity pneumonitis-like syndrome associated with the use of lenalidomide.

Chest 2007 May;131;1572-4 — 2007 May — 1572-4