The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XX.h

Nontuberculous pulmonary mycobacterial infection/superinfection

Publications

Dal Molín-Veglia MA, Sánchez-Martínez F, Fernández-Alarza AF, Domínguez-Álvarez M

Pulmonary Mycobacteriosis in a Patient Receiving Chronic Methotrexate Treatment.

Archivos de bronconeumologia 2018 Apr;54;225-226 — 2018 Apr — 225-226

Park JS, Jung ES, Choi W, Park SY, Rim MY, Yu I, Park H, Lee SM, Park JW, Jeong SH, Lee SP, Park S

Mycobacterium intracellulare Pulmonary Disease with Endobronchial Caseation in a Patient Treated with Methotrexate.

Tuberculosis and respiratory diseases 2013 Jul;75;28-31 — 2013 Jul — 28-31

Mori S, Imamura F, Koga Y, Uramoto H, Ezaki T, Sugimoto M

Pulmonary Mycobacterium abscessus disease in a patient receiving low-dose methotrexate for treatment of early rheumatoid arthritis.

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 2013 Dec;19;1146-51 — 2013 Dec — 1146-51