The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Cyanosis, a low SpO2 and normal measured PaO2
See under XIVa: Methemoglobinemia
Publications
Blue fingers and lips on an acute medical take.
The New Zealand medical journal 2009 May 22;122;65-6 — 2009 May 22 — 65-6
Near-fatal methemoglobinemia after recreational inhalation of amyl nitrite aerosolized with a compressed gas blower.
Journal of the Formosan Medical Association = Taiwan yi zhi 2005 Nov;104;856-9 — 2005 Nov — 856-9
[Amyl nitrite poisoning].
Ugeskrift for laeger 1998 Jun 15;160;3740-1 — 1998 Jun 15 — 3740-1
A case of methaemoglobinaemia.
Archives of emergency medicine 1993 Jun;10;117-9 — 1993 Jun — 117-9
A case of cyanosis without hypoxemia.
Journal of the Tennessee Medical Association 1990 Jan;83;22 — 1990 Jan — 22