The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

X.a

DRES syndrome - DRESS-like reaction

Publications

Chaabane A, Ben Fadhel N, Chadli Z, Ben Fredj N, Boughattas NA, Aouam K

Phenobarbital-induced DRESS: a lichenoïd picture.

Iranian journal of allergy, asthma, and immunology. 2014;13(6):453-5

Giri PP, Roy S, Bhattyacharya S, Pal P, Dhar S

Dress syndrome with sepsis, acute respiratory distress syndrome and pneumomediastinum.

Indian journal of dermatology. 2011;56(6):763-5

Arima M, Kanoh T, Yamasaki A, Matsuda S, Kasuya H, Sunayama S, Kawai S, Okada R

Eosinophilic myocarditis associated with toxicodermia caused by phenobarbital.

Japanese circulation journal. 1998;62(2):132-5