The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Vascultis (pulmonary, extrathoracic or systemic)-ANCA status unknown or negative)
May also be a manifestation in RA unexposed to drugs
Publications
Etanercept-induced Henoch-Schönlein purpura in a patient with ankylosing spondylitis.
Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 2013 Mar;19;90-3 — 2013 Mar — 90-3
Accelerated nodulosis and vasculitis following etanercept therapy for rheumatoid arthritis.
Arthritis and rheumatism 2002 Aug;47;445-9 — 2002 Aug — 445-9