The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Path: Obliterative (constrictive) bronchiolitis (see also IVc, IVn)
Publications
Retransplantation of contralateral lung in a patient with Sauropus androgynus-induced bronchobronchiolitis obliterans.
Transplantation proceedings 2000 Nov;32;2432-4 — 2000 Nov — 2432-4
Sauropus androgynus-constrictive obliterative bronchitis/bronchiolitis--histopathological study of pneumonectomy and biopsy specimens with emphasis on the inflammatory process and disease progression.
Histopathology 2000 Nov;37;402-10 — 2000 Nov — 402-10
Segmental necrosis of small bronchi after prolonged intakes of Sauropus androgynus in Taiwan.
American journal of respiratory and critical care medicine 1998 Feb;157;594-8 — 1998 Feb — 594-8
Histopathological study of Sauropus androgynus-associated constrictive bronchiolitis obliterans: a new cause of constrictive bronchiolitis obliterans.
The American journal of surgical pathology 1997 Jan;21;35-42 — 1997 Jan — 35-42