The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

I.a

Pneumonitis (interstitial lung disease/ILD)

Publications

Ratnapala US, Yucel-Finn A, Walbaum D, Dempsey O

A puzzling pneumonia in a young immunosuppressed man.

BMJ case reports 2018 Apr 17;2018; — 2018 Apr 17

Haro Estarriol M, Rubio Goday M, Puig J

[Pulmonary disease associated with fluoxetine administration].

Archivos de bronconeumologia 2002 Mar;38;153 — 2002 Mar — 153

Braun D, Nippert B, Loeuille D, Blain H, Tréchot P

[Interstitial pneumopathy induced by fluoxetine].

La Revue de medecine interne 1999 Oct;20;949-50 — 1999 Oct — 949-50

de Kerviler E, Trédaniel J, Revlon G, Groussard O, Zalcman G, Ortoli JM, Espié M, Hirsch A, Frija J

Fluoxetin-induced pulmonary granulomatosis.

The European respiratory journal 1996 Mar;9;615-7 — 1996 Mar — 615-7

Gonzalez-Rothi RJ, Zander DS, Ros PR

Fluoxetine hydrochloride (Prozac)-induced pulmonary disease.

Chest 1995 Jun;107;1763-5 — 1995 Jun — 1763-5