The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XV.c

Path: Organizing pneumonia (OP/BOOP) pattern (see also Id)

Publications

Cho SK, Oh IH, Park CK, Bae SC, Sung YK

Etanercept induced organizing pneumonia in a patient with rheumatoid arthritis.

Rheumatology international 2012 Apr;32;1055-7 — 2012 Apr — 1055-7

Hsu PC, Lan JL, Hsieh TY, Jan YJ, Huang WN

Methotrexate pneumonitis in a patient with rheumatoid arthritis.

Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 2003 Jun;36;137-40 — 2003 Jun — 137-40