The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Anaphylaxis-Anaphylactoid reaction (can be fatal)
Publications
Management and preparedness for infusion and hypersensitivity reactions.
The oncologist 2007 May;12;601-9 — 2007 May — 601-9
IgE-mediated anaphylaxis after first intravenous infusion of cyclosporine.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2001 Sep;87;243-5 — 2001 Sep — 243-5