The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

X.a

DRES syndrome - DRESS-like reaction

Publications

Schmutz JL, Barbaud A, Tréchot P

[Hydroxychloroquine and DRESS].

Annales de dermatologie et de venereologie 2008 Dec;135;903 — 2008 Dec — 903

Volpe A, Marchetta A, Caramaschi P, Biasi D, Bambara LM, Arcaro G

Hydroxychloroquine-induced DRESS syndrome.

Clinical rheumatology 2008 Apr;27;537-9 — 2008 Apr — 537-9