The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLIV.a

Angioedema (may cause UAO, asphyxia and death)

Publications

Andrew N, Gabb G, Del Fante M

ACEI associated angioedema - a case study and review.

Australian family physician 2011 Dec;40;985-8 — 2011 Dec — 985-8

Karagiannis A, Pyrpasopoulou A, Tziomalos K, Florentin M, Athyros V

Angioedema may not be a class side-effect of the angiotensin-converting-enzyme inhibitors.

QJM : monthly journal of the Association of Physicians 2006 Mar;99;197-8 — 2006 Mar — 197-8