The Drug-Induced Respiratory Disease Website and App

Radiation therapy, infusional (injected 131I or 90Y radioactivity)

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

I.a

Pneumonitis (interstitial lung disease/ILD)

Publications

Dobrocky T, Fuerstner M, Klaeser B, Lopez-Benitez R, Wälti YB, Kara L

Regional Radiation Pneumonitis After SIRT of a Subcapsular Liver Metastasis: What is the Effect of Direct Beta Irradiation?

Cardiovascular and interventional radiology 2015 Aug;38;1025-30 — 2015 Aug — 1025-30

Wright CL, Werner JD, Tran JM, Gates VL, Rikabi AA, Shah MH, Salem R

Radiation pneumonitis following yttrium-90 radioembolization: case report and literature review.

Journal of vascular and interventional radiology : JVIR 2012 May;23;669-74 — 2012 May — 669-74