The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Bronchospasm - Wheezing - Asthma
Publications
Successful rechallenge with etoposide phosphate after an acute hypersensitivity reaction to etoposide.
Pharmacotherapy 1999 Aug;19;989-91 — 1999 Aug — 989-91
Hudson MM, Weinstein HJ, Donaldson SS, Greenwald C, Kun L, Tarbell NJ, Humphrey WA, Rupp C, Marina NM, Wilimas J
Acute hypersensitivity reactions to etoposide in a VEPA regimen for Hodgkin's disease.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1993 Jun;11;1080-4 — 1993 Jun — 1080-4
Hypersensitivity reactions induced by etoposide.
Cancer treatment reports 1984 Jul-Aug;68;959-61 — 1984 Jul-Aug — 959-61