The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

LVIII.e

Path: Acute fibrinous organizing pneumonia (AFOP-pattern) (see also If)

Alghough not explicitely stated in these 2 papers, authors confirmed thir respective patient was on a statin

Publications

Tzouvelekis A, Koutsopoulos A, Oikonomou A, Froudarakis M, Zarogoulidis P, Steiropoulos P, Mikroulis D, Antoniades A, Bouros D

Acute fibrinous and organising pneumonia: a case report and review of the literature.

Journal of medical case reports 2009 Oct 12;3;74 — 2009 Oct 12 — 74

Bhatti S, Hakeem A, Torrealba J, McMahon JP, Meyer KC

Severe acute fibrinous and organizing pneumonia (AFOP) causing ventilatory failure: successful treatment with mycophenolate mofetil and corticosteroids.

Respiratory medicine 2009 Nov;103;1764-7 — 2009 Nov — 1764-7