The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Severe or catastrophic bronchospasm or asthma attack (can be fatal)
Publications
Rituximab as induction therapy in relapsing eosinophilic granulomatosis with polyangiitis: A report of 6 cases.
Joint, bone, spine : revue du rhumatisme 2016 Jan;83;81-4 — 2016 Jan — 81-4
Severe bronchospasm associated with rituximab for refractory Churg-Strauss syndrome.
Annals of the rheumatic diseases 2009 Apr;68;606 — 2009 Apr — 606
Infusion reactions associated with the therapeutic use of monoclonal antibodies in the treatment of malignancy.
Cancer metastasis reviews 1999;18;465-71 — 1999 — 465-71