The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

X.f

Anaphylaxis-Anaphylactoid reaction (can be fatal)

Publications

Chalise SN, Palmer E, Pathak V

Fatal Allergic Reaction to Gadolinium Contrast.

Cureus. 2023;15(7):e42455

Renaudin JM, Beaudouin E, Ponvert C, Demoly P, Moneret-Vautrin DA

Severe drug-induced anaphylaxis: analysis of 333 cases recorded by the Allergy Vigilance Network from 2002 to 2010.

Allergy. 2013;68(7):929-37

Jung JW, Kang HR, Kim MH, Lee W, Min KU, Han MH, Cho SH

Immediate hypersensitivity reaction to gadolinium-based MR contrast media.

Radiology. 2012;264(2):414-22

Prince MR, Zhang H, Zou Z, Staron RB, Brill PW

Incidence of immediate gadolinium contrast media reactions.

AJR. American journal of roentgenology. 2011;196(2):W138-43

Murphy KJ, Brunberg JA, Cohan RH

Adverse reactions to gadolinium contrast media: a review of 36 cases.

AJR. American journal of roentgenology. 1996;167(4):847-9