The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

LVIII.aa

Path: Endogenous lipoid pneumonia (phospholipidosis)

Publications

Huang LK, Tsai MJ, Tsai HC, Chao HS, Lin FC, Chang SC

Statin-induced lung injury: diagnostic clue and outcome.

Postgraduate medical journal 2013 Jan;89;14-9 — 2013 Jan — 14-9

Wang CW, Colby TV

Histiocytic lesions and proliferations in the lung.

Seminars in diagnostic pathology 2007 Aug;24;162-82 — 2007 Aug — 162-82

Lantuejoul S, Brambilla E, Brambilla C, Devouassoux G

Statin-induced fibrotic nonspecific interstitial pneumonia.

The European respiratory journal 2002 Mar;19;577-80 — 2002 Mar — 577-80