The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Path: NSIP-cellular pattern (see also Ia, Ib)
Publications
Gold-induced pulmonary disease: clinical features, outcome, and differentiation from rheumatoid lung disease.
American journal of respiratory and critical care medicine 1997 Mar;155;1011-20 — 1997 Mar — 1011-20
Pneumonitis caused by gold salt therapy: evidence for the role of cell-mediated immunity in its pathogenesis.
The American review of respiratory disease 1980 Jul;122;145-52 — 1980 Jul — 145-52