The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
ARDS - Acute lung injury
Publications
Life-Threatening Docetaxel Toxicity in a Patient With Reduced-Function CYP3A Variants: A Case Report.
Frontiers in oncology 2021;11;809527 — 2021 — 809527
Lungs in White Induced by Docetaxel.
The Israel Medical Association journal : IMAJ 2017 06;19;393-394 — 2017 06 — 393-394
Acute respiratory distress syndrome mimickers lacking common risk factors of the Berlin definition.
Intensive care medicine 2016 Feb;42;164-72 — 2016 Feb — 164-72
Acute Respiratory Distress Syndrome after Treatment of Metastatic Prostate Cancer with Taxotere: A Case Report and Literature Review.
Case reports in urology 2015;2015;198381 — 2015 — 198381
Fatal hypersensitivity pneumonitis associated with docetaxel.
Tumori 2013 May-Jun;99;e100-3 — 2013 May-Jun — e100-3
Lethal pneumonitis after docetaxel chemotherapy: case report and review of the literature.
Acta oncologica (Stockholm, Sweden) 2013 Jun;52;1034-8 — 2013 Jun — 1034-8
Docetaxel-induced fatal interstitial pneumonitis in a patient with castration-resistant prostate cancer.
Korean journal of urology 2012 May;53;371-4 — 2012 May — 371-4
Fatal pneumonitis after treatment with docetaxel and trastuzumab.
The Netherlands journal of medicine 2009 Jun;67;237-9 — 2009 Jun — 237-9
Acute lung injury associated with docetaxel and bevacizumab.
Clinical oncology (Royal College of Radiologists (Great Britain)) 2007 Dec;19;803-5 — 2007 Dec — 803-5
Leimgruber K, Negro R, Baier S, Moser B, Resch G, Sansone S, Adami M, Zanon P, Graiff C, Egarter-Vigl E, Wiedermann CJ
Fatal interstitial pneumonitis associated with docetaxel administration in a patient with hormone-refractory prostate cancer.
Tumori 2006 Nov-Dec;92;542-4 — 2006 Nov-Dec — 542-4
[Docetaxel-induced acute pulmonary capillary-leak syndrome mimicking cardiogenic oedema].
Annales francaises d'anesthesie et de reanimation 2007 Feb;26;180-1 — 2007 Feb — 180-1
Fatal respiratory failure associated with treatment of prostate cancer using docetaxel and estramustine.
Urology 2002 Dec;60;1111 — 2002 Dec — 1111
Severe interstitial pneumonitis associated with docetaxel administration.
Cancer 2002 Feb 01;94;847-53 — 2002 Feb 01 — 847-53
Life-threatening hypersensitivity pneumonitis induced by docetaxel (taxotere).
British journal of cancer 2001 Nov 02;85;1247-50 — 2001 Nov 02 — 1247-50