The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

V.m

Pleuropericarditis - Pleuropericardial effusion (ANA unknown or negative)

Publications

Demir UF

Valproic acid associated pleuropericardial effusion: case report.

Ideggyogyaszati szemle 2020 Jan 30;73;70-72 — 2020 Jan 30 — 70-72

Tonnelier JM, Mocquard Y, Broch C, Vandhuick O, Goas P, Goas JY

[Febrile pleuropericarditis during valproic acid treatment].

Presse medicale (Paris, France : 1983) 2001 Jan 20;30;62-3 — 2001 Jan 20 — 62-3