The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLI.e

ARDS - Acute lung injury

Publications

Ata F, Shaher Mousa Hussein M, Mismar AY, Sharma R, Bozom IAM, Alsiddig Ali Ibrahim Z, Ibrahim WH

Rifampicin-Induced Pneumonitis Mimicking Severe COVID-19 Pneumonia Infection.

The American journal of case reports 2020 Aug 25;21;e927586 — 2020 Aug 25 — e927586

Ashitani J, Yanagi S, Arimura Y, Sano A, Mukae H

Acute respiratory distress syndrome induced by rifampicin with high levels of neutrophil and eosinophil products in bronchoalveolar lavage fluid.

Respiration; international review of thoracic diseases 2003 Sep-Oct;70;541-3 — 2003 Sep-Oct — 541-3