The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

X.a

DRES syndrome - DRESS-like reaction

Publications

Fleming P, Marik PE

The DRESS syndrome: the great clinical mimicker.

Pharmacotherapy. 2011;31(3):332

Jurado-Palomo J, Cabañas R, Prior N, Bobolea ID, Fiandor-Román AM, López-Serrano MC, Quirce S, Bellón T

Use of the lymphocyte transformation test in the diagnosis of DRESS syndrome induced by ceftriaxone and piperacillin-tazobactam: two case reports.

Journal of investigational allergology & clinical immunology. 2010;20(5):433-6

Fahim S, Jain V, Victor G, Pierscianowski T

Piperacillin-tazobactam-induced drug hypersensitivity syndrome.

Cutis. 2006;77(6):353-7

Cabañas R, Muñoz L, López-Serrano C, Contreras J, Padial A, Caballero T, Moreno-Ancillo A, Barranco P

Hypersensitivity to piperacillin.

Allergy. 1998;53(8):819-20