The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)
Publications
Pulmonary complications following tricyclic antidepressant overdose in an adolescent.
The Annals of pharmacotherapy 1993 May;27;572-4 — 1993 May — 572-4
Desipramine-induced pulmonary interstitial eosinophilia.
Drug intelligence & clinical pharmacy 1982 Dec;16;966-7 — 1982 Dec — 966-7
Massive eosinophilic reaction to desipramine in conjunction with pneumonia.
Canadian journal of psychiatry. Revue canadienne de psychiatrie 1984 Mar;29;142-4 — 1984 Mar — 142-4