The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

I.c

Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

Imaging features e.g.: PMID : 23996619

Publications

Poschenrieder F, Schulz C, Hamer OW

[Eosinophilic pneumonia toxicity induced by Dapsone].

RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin 2014 Feb;186;178-9 — 2014 Feb — 178-9

Adar T, Tayer-Shifman O, Mizrahi M, Tavdi S, Barak O, Shalit M

Dapsone induced eosinophilic pneumonia.

European annals of allergy and clinical immunology 2012 Jun;44;144-6 — 2012 Jun — 144-6

Kaur J, Khandpur S, Seith A, Khanna N

Dapsone-induced eosinophilic pneumonitis in a leprosy patient.

Indian journal of leprosy 2005 Jul-Sep;77;267-71 — 2005 Jul-Sep — 267-71

Arunthathi S, Raju S

Dapsone induced pulmonary eosinophilia without cutaneous allergic manifestations--an unusual encounter--a case report.

Acta leprologica 1998;11;3-5 — 1998 — 3-5

Jaffuel D, Lebel B, Hillaire-Buys D, Pene J, Godard P, Michel FB, Blayac JP, Bousquet J, Demolyi P

Eosinophilic pneumonia induced by dapsone.

BMJ (Clinical research ed.) 1998 Jul 18;317;181 — 1998 Jul 18 — 181

Janier M, Guillevin L, Badillet G

Pulmonary eosinophilia associated with dapsone.

Lancet (London, England) 1994 Apr 02;343;860-1 — 1994 Apr 02 — 860-1