The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

I.b

Pneumonitis (interstitial lung disease/ILD)

Publications

Boudewijns S, Westdorp H, Koornstra RH, Aarntzen EH, Schreibelt G, Creemers JH, Punt CJ, Figdor CG, de Vries IJ, Gerritsen WR, Bol KF

Immune-related Adverse Events of Dendritic Cell Vaccination Correlate With Immunologic and Clinical Outcome in Stage III and IV Melanoma Patients.

Journal of immunotherapy (Hagerstown, Md. : 1997) 2016 Jul-Aug;39;241-8 — 2016 Jul-Aug — 241-8

Watanabe S, Waseda Y, Takato H, Inuzuka K, Katayama N, Kasahara K, Fujimura M

Influenza vaccine-induced interstitial lung disease.

The European respiratory journal 2013 Feb;41;474-7 — 2013 Feb — 474-7

Umeda Y, Morikawa M, Anzai M, Sumida Y, Kadowaki M, Ameshima S, Ishizaki T

Acute exacerbation of idiopathic pulmonary fibrosis after pandemic influenza A (H1N1) vaccination.

Internal medicine (Tokyo, Japan) 2010;49;2333-6 — 2010 — 2333-6

Heinrichs D, Sennekamp J, Kirsten A, Kirsten D

[Allergic alveolitis after influenza vaccination].

Pneumologie (Stuttgart, Germany) 2009 Sep;63;508-11 — 2009 Sep — 508-11

Johnston SD, Kempston A, Robinson TJ

Pneumonitis secondary to the influenza vaccine.

Postgraduate medical journal 1998 Sep;74;541-2 — 1998 Sep — 541-2