The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Eosinophilic pleural effusion
Publications
Eosinophilic exudative pleural effusion after initiation of tizanidine treatment: a case report.
Pain medicine (Malden, Mass.) 2003 Mar;4;85-90 — 2003 Mar — 85-90
Pleuropericardial reaction to treatment with dantrolene.
JAMA 1979 Dec 21;242;2772-4 — 1979 Dec 21 — 2772-4