The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLIX.d

Lupus - Lupus syndrome (see also Vd)

Publications

Arnaud L, Mertz P, Gavand PE, Martin T, Chasset F, Tebacher-Alt M, Lambert A, Muller C, Sibilia J, Lebrun-Vignes B, Salem JE

Drug-induced systemic lupus: revisiting the ever-changing spectrum of the disease using the WHO pharmacovigilance database.

Annals of the rheumatic diseases 2019 04;78;504-508 — 2019 04 — 504-508

Rubin RL

Drug-induced lupus.

Toxicology 2005 Apr 15;209;135-47 — 2005 Apr 15 — 135-47

KAPLAN JM, WACHTEL HL, CZARNECKI SW, SAMPSON JJ

LUPUS-LIKE ILLNESS PRECIPITATED BY PROCAINAMIDE HYDROCHLORIDE.

JAMA 1965 May 10;192;444-7 — 1965 May 10 — 444-7

LADD AT

Procainamide-induced lupus erythematosus.

The New England journal of medicine 1962 Dec 27;267;1357-8 — 1962 Dec 27 — 1357-8

London BL, Pincus I

Reversible lupus-like illness induced by procainamide.

American heart journal 1966 Dec;72;806-8 — 1966 Dec — 806-8

Blomgren SE, Condemi JJ, Bignall MC, Vaughan JH

Antinuclear antibody induced by procainamide. A prospective study.

The New England journal of medicine 1969 Jul 10;281;64-6 — 1969 Jul 10 — 64-6

Rubin RL, Nusinow SR, Johnson AD, Rubenson DS, Curd JG, Tan EM

Serologic changes during induction of lupus-like disease by procainamide.

The American journal of medicine 1986 May;80;999-1002 — 1986 May — 999-1002

Mongey AB, Donovan-Brand R, Thomas TJ, Adams LE, Hess EV

Serologic evaluation of patients receiving procainamide.

Arthritis and rheumatism 1992 Feb;35;219-23 — 1992 Feb — 219-23