The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

VI.a

Pleural effusion (uni- or bilateral) (can accompany DI-LDs)

Publications

Wright P

Untoward effects associated with practolol administration: oculomucocutaneous syndrome.

British medical journal 1975 Mar 15;1;595-8 — 1975 Mar 15 — 595-8

Hall DR, Morrison JB, Edwards FR

Pleural fibrosis after practolol therapy.

Thorax 1978 Dec;33;822-4 — 1978 Dec — 822-4

Lemola M, Ahonen A

[Bilateral pleural effusion after practolol (author's transl)].

Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis 1977 May 31;66;676-8 — 1977 May 31 — 676-8

MacKAY AD, Axford AT

Letter: Pleural effusions after practolol.

Lancet (London, England) 1976 Jan 10;1;89 — 1976 Jan 10 — 89

Fleming HA, Hickling P

Letter: Pleural effusions after practolol.

Lancet (London, England) 1975 Dec 13;2;1202 — 1975 Dec 13 — 1202