The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

X.a

DRES syndrome - DRESS-like reaction

Publications

Pereira de Silva N, Piquioni P, Kochen S, Saidon P

Risk factors associated with DRESS syndrome produced by aromatic and non-aromatic antipiletic drugs.

European journal of clinical pharmacology. 2011;67(5):463-70

Marik P

Anticonvulsant hypersensitivity syndrome occurring as sepsis with multiorgan dysfunction.

Pharmacotherapy. 1999;19(3):346-8

Angle P, Thomas P, Chiu B, Freedman J

Bronchiolitis obliterans with organizing pneumonia and cold agglutinin disease associated with phenytoin hypersensitivity syndrome.

Chest. 1997;112(6):1697-9