The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)
Publications
Unilateral balsalazide-induced eosinophilic pneumonia in an ulcerative colitis patient.
The journal of the Royal College of Physicians of Edinburgh 2010 Sep;40;216-8 — 2010 Sep — 216-8
Case records of the Massachusetts General Hospital. Case 33-2008. A 63-year-old woman with dyspnea on exertion.
The New England journal of medicine 2008 Oct 23;359;1823-32 — 2008 Oct 23 — 1823-32